Distraught by fear and despair, he could not find his way.

He felt a surge of hope, followed immediately by despair.

They are the people living in poverty and surrounded by despair and drugs.

At once I was back in the mine, swallowed up by darkness and despair.

Something brought on by exposure and despair at ever being rescued.

She had become that, her magic fed by rage and despair.

She must be dreaming, driven out of her mind by despair.

His steps slowed, dragged down by the wet and by despair.

Moore came to a sudden halt beside his car and stood there, paralyzed by despair.

But whether by plan or despair, the best he could come up with was wait and see what else happened.