As the story goes, she was in a period of deep despair.

In every case, I was looking at the face of despair.

I had met one years ago and the look of despair in his eyes would never leave me.

Since last night I have a feeling of such despair.

But all the same I was almost in a state of despair.

The most important thing is not to drive these people to a situation of despair.

He went through a period of despair after his wife left him.

My mind seemed to be in a state of despair.

When he went down, it was with a sense of despair.

The scene they had found was one of total despair.