be in despair

She looked from one to the other of them in despair.

Several times during the next few hours she almost gave up in despair.

By 1889 they were in despair and looked for change from their problems.

Everything was being taken from her, she thought in despair.

When a month had gone by, I was almost in despair.

In his despair, he began to see the truth about himself.

Tom and his friends were in despair at this news.

I don't want to love him, she thought in despair.

Doesn't do what's expected of it and you give up in despair.

We must bring hope to large parts of the world that have to live in despair.