In pharmacology, the minimal effective concentration, i.e., the smallest concentration of a drug that will induce the desired pharmacological effect.
The minimal concentration of nonionic detergent required to release cytosolic components without disrupting nuclei was determined by measuring lactate dehydrogenase activity as a marker for release of cytosol.
VaTx2 becomes effective on Kv2 at a minimal concentration of 40 μM.
In the body it is converted to the human physiological forms methylcobalamin and adenosylcobalamin, leaving behind the cyanide, albeit in minimal concentration.
He fumigated plants with known amount of several chemical compounds, for example sulfur dioxide, to detect the minimal concentration at which damages occurs.
Studies show minimal concentrations of clotrimazole cause leakage of intracellular phosphorus compounds into the ambient medium, along with the breakdown of cellular nucleic acids and an accelerated K efflux.
Thus, it is actually a median value; the use of minimum would appear to be descended from the original paper in which the concept appeared, although the term there was minimal alveolar concentration.
CRE can be difficult to detect because some strains that harbor blakpc have minimal inhibitory concentrations (MICs) that are elevated but still within the susceptible range for carbapenems.
Susceptibility thresholds for clarithromycin are minimal inhibitory concentrations of 32 g/mL and a minimal inhibitory concentration of 256 g/mL for azithromycin (207).
In the case of the steady-state conditions described above, the catalyst resting state is the unbound form (because the substrate-bound intermediate is, by definition, only present at a minimal concentration.)