The alpha subunit, now free to move along the inner membrane, eventually contacts another membrane-bound protein - the "primary effector."
It is however known that in yeast post-translational translocation requires the translocon and two additional membrane-bound proteins, Sec62 and Sec63.
TRAIL can be expressed as a membrane-bound protein or solubilized by metalloendoproteinase cleavage.
Microsomal CPR is membrane-bound protein that interacts with different P450s.
However, a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted.
Certain membrane-bound proteins are targeted to the secretory pathway by their first transmembrane domain, which resembles a typical signal peptide.
It is therefore called a membrane-bound protein.
RRBP1 (also known as p180), a human gene that encodes a membrane-bound protein of the endoplasmic reticulum.
This domain is present in a large number of membrane-bound and extracellular, mostly animal, proteins.
This pathway is poorly understood in eukaryotes, but is facilitated by Sec62 and Sec63, two membrane-bound proteins.