The gene for membrane cofactor protein is the next target.

Mutations in the complement regulators factor H and membrane cofactor protein have been associated with atypical haemolytic uraemic syndrome.

Membrane cofactor protein (MCP or CD46)

The hyperacute rejection reaction is known to be mediated by complement which in itself is regulated by a family of membrane glycoproteins including decay-accelerating factor (DAF) and membrane cofactor protein.

CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene.

The complement system activation may be due to mutations in the complement regulatory proteins (factor H, factor I, or membrane cofactor protein), or is occasionally due to acquired neutralizing autoantibody inhibitors of these complement system components, for example anti-factor H antibodies.

A rare subset of this disease (referred to as atypical haemolytic uraemic syndrome, aHUS), has been strongly linked to mutations in genes of the complement system (including factor H, factor I and membrane cofactor protein), with the factor H mutations being the most numerous.

"A male chauvinist pig who's going to drive you up a wall."

"He is everything and a male chauvinist pig to boot."

So he had cleaned up himself Take that, male chauvinist pig!

For the first time in my life I was ashamed of being a male chauvinist pig.

The term "male chauvinist pig" was probably invented with them in mind.

Because he, like me, was a male chauvinist pig.

"And some of you are just male chauvinist pigs."

Well, Alan fitted the bill: the classic male chauvinist pig.

"Male chauvinist pig," she called to his back as he headed off to the Commons that morning.

That's just a queen's way of being a male chauvinist pig!"

"There are a lot of male chauvinist pigs out there," she says.

"They weren't trying to rule countries dominated by male chauvinist pigs."

He was being a male chauvinist pig, that's what, and she wouldn't permit it.

"Well, if you do, try not to phrase the praise in such male chauvinist pig terms.

"Until the 1970's, it was expected that men were male chauvinist pigs," he said.

"Are these weirdos what the psych books call male chauvinist pigs?"

Bond - whatever male chauvinist pig means, dratted bad use of language if you ask me.

"I fear you're in the process of becoming what is called a male chauvinist pig.'

Dawson also called Darren "an opportunist" and a "male chauvinist pig".

"One more word of that male chauvinist pig dreck and I will claw your eyes out."

And you are a male chauvinist pig!"

HE'S always been a bully and a lout, but now, more than ever, the male chauvinist pig in him is showing.

So I had to come as well or be the perfect Male Chauvinist Pig.

"As they say, a male chauvinist pig."

'Not simply superstitious, but a solid male chauvinist pig, I'd say.