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These findings suggest that, in the ovine fetus, hypothalamic releasing hormones can be transported directly via a portal vascular way to the pituitary gland that develops as early as 45 days of gestation.
The work on TRH strongly supported that additional hypothalamic releasing hormones would be discovered which was accomplished within the next 2 years with the discovery of LHRH by Dr. Schally's group and others followed in subsequent years.
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