An estimated quarter of a million American men are now taking the hormone.
As of 2009, an estimated quarter of Earth's population uses the services of the Internet.
An estimated quarter of a billion cubes were sold between 1980 and 1985.
During the 1920s and 1930s the Soviet authorities resettled an estimated quarter of a million Russians in the region.
An estimated quarter of a millions fans cheered as he crossed the finish line.
An estimated quarter of Spain's population, 11 million people, poured onto the streets in demonstrations of peace and solidarity the following day.
Each year it performs to a total audience of around 60,000, an estimated quarter of whom come from abroad.
An estimated quarter of the world's undiscovered oil and gas resources are in the Arctic.
An estimated quarter of the 10,000 expected demonstrators initially turned up after Scotland Yard announced 4,000 officers had been made available.
In total, the loss cost Haynes an estimated quarter of his net worth.