C5b forms the first part of the complement membrane attack complex.

SP-40, 40 is associated with the assembly of the membrane attack complex of human complement.

Secondly, some complement system components form a membrane attack complex to assist antibodies to kill the bacterium directly.

In lieu of the membrane attack complex, complement proteins (particularly C3b and C4b) are deposited on red blood cells.

It is part of the membrane attack complex which can insert into the cell membrane and cause cell to lyse.

If the complement response is sufficient, red blood cells are damaged by the membrane attack complex, an effector of the complement cascade.

The subsequent complement cascade catalyzed by C3-convertase results in creating a membrane attack complex, which causes lysis of the pathogen.

A cluster of proteins called the membrane attack complex, which normally attack only foreign particles, suddenly attacks cells that line the inside of vessels.

C8 alpha-gamma induces the polymerization of 10-16 molecules of C9 into a pore-forming structure known as the membrane attack complex.

That is, mediators of acute inflammation are generated at the site and membrane attack complexes cause cell lysis and death.

One example is CD59, also known as protectin, which inhibits C9 polymerisation during the formation of the membrane attack complex.

Activation of complements occurs far from the cell membrane, and insertion of the membrane attack complex does not occur.

Terminal complement pathway deficiency is a genetic condition affecting the complement membrane attack complex (MAC).

The membrane attack complex is initiated when the complement protein C5 convertase cleaves C5 into C5a and C5b.

The proteolytic cleavage of C5 is the only known enzymatic event in assembly of the cytolytic membrane attack complex of complement.

It is a member of the Membrane Attack Complex (MAC) and induces pores on membranes.

If the complement response is insufficient to form membrane attack complexes, then extravascular lysis will be favored over intravascular red blood cell lysis.

The worms have many tools that help in this evasion, including the tegument, antioxidant proteins, and defenses against host membrane attack complex (MAC).

The C5b then recruits and assembles C6, C7, C8 and multiple C9 molecules to assemble the membrane attack complex.

The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex.

A C5,6,7,8,9 (the MAC, membrane attack complex, or terminal complement proteins) deficiency lead to unopposed Neisserial infections.

The complement proteins C6-C9 all contain a MACPF domain and assemble into the membrane attack complex.

When complement activation leads to deposition of C5b678 on host cells, CD59 can prevent C9 from polymerizing and forming the complement membrane attack complex.

Quinidine (IgM mediated activation of classical complement pathway and Membrane attack complex, MAC)

CFHR1 blocks C5 convertase activity and interferes with C5b surface deposition and membrane attack complex (MAC) formation.

It is a potent anesthetic with a minimum alveolar concentration of 0.74.

Further research into the possible mechanisms of narcosis by anesthetic action led to the "minimum alveolar concentration" concept in 1965.

Volatile agents are frequently compared in terms of potency, which is inversely proportional to the minimum alveolar concentration.

With a minimum alveolar concentration (MAC) of 0.2%, methoxyflurane is an extremely potent anesthetic agent.

However, the minimum alveolar concentration (MAC) for nitrogen is not achieved until pressures of about 20 to 30 atm (bar) are attained.

Cyclopropane is a relatively potent, non-irritating and sweet smelling agent with a minimum alveolar concentration of 17.5% and a blood/gas partition coefficient of 0.55.

In fact, newer volatile agents (e.g., sevoflurane, desflurane) have been popular not due to their potency (minimum alveolar concentration), but due to their versatility for a faster emergence from anesthesia, thanks to their lower blood-gas partition coefficient.

(Note: "MAC hour" is the multiple of the minimum alveolar concentration (MAC) of the anesthetic used times the number of hours the drug is administered, a measure of the dosage of inhaled anesthetics.)

The authors showed that subclinical nephrotoxicity occurred following methoxyflurane at minimum alveolar concentration (MAC) for 2.5 to 3 hours (2.5 to 3 MAC hours), while overt toxicity was present in all patients at dosages greater than five MAC hours.

Minimum alveolar concentration or MAC is a concept used to compare the strengths, or potency, of anaesthetic vapours; in simple terms, it is defined as the concentration of the vapour in the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus.

In many ways the Mac is not better, just different.

Mac has been having some problem in the last week.

I have not found anything as good on the Mac.

Hours later she once again found herself alone in a room with Mac.

He and Mac heard the phone at the same time.

Now Mac for sure heard a voice from the back.

We pretty much know what will be in the next Mac.

I am getting the Mac for free, if you will.

The 7300 is the same as on my Mac at work.

Well, state of the art for a Mac around 1990.

Even more, he needed the time spent with Mac and his wife.

God help her, what she was going to do with him and Mac?

Mac is going out with me today to her house.

By then, Mac has come to terms with his situation and is ready to move on.

Mac and I go back a ways, you know that.

And really that should be turned off on the Mac.

And yes, it will even be available on the Mac.

It is on a Mac, so what are you even talking about?

All of this has been possible on the Mac as well.

Are you using it on a mac by any chance?

If the woman had shot Mac, she would have done it.

Mac looked up at me, as I stood before him.

Mac thought, a whole five days and they'd come no further than this.

I use my Mac all the time - more or less 24 hours a day.

She could see so much more now that they were no longer with Mac.

In many ways the Mac is not better, just different.

Mac has been having some problem in the last week.

I have not found anything as good on the Mac.

Hours later she once again found herself alone in a room with Mac.

He and Mac heard the phone at the same time.

Now Mac for sure heard a voice from the back.

We pretty much know what will be in the next Mac.

I am getting the Mac for free, if you will.

The 7300 is the same as on my Mac at work.

Well, state of the art for a Mac around 1990.

Even more, he needed the time spent with Mac and his wife.

God help her, what she was going to do with him and Mac?

Mac is going out with me today to her house.

By then, Mac has come to terms with his situation and is ready to move on.

Mac and I go back a ways, you know that.

And really that should be turned off on the Mac.

And yes, it will even be available on the Mac.

It is on a Mac, so what are you even talking about?

All of this has been possible on the Mac as well.

Are you using it on a mac by any chance?

If the woman had shot Mac, she would have done it.

Mac looked up at me, as I stood before him.

Mac thought, a whole five days and they'd come no further than this.

I use my Mac all the time - more or less 24 hours a day.

She could see so much more now that they were no longer with Mac.

In many ways the Mac is not better, just different.

Mac has been having some problem in the last week.

I have not found anything as good on the Mac.

Hours later she once again found herself alone in a room with Mac.

He and Mac heard the phone at the same time.

Now Mac for sure heard a voice from the back.

We pretty much know what will be in the next Mac.

I am getting the Mac for free, if you will.

The 7300 is the same as on my Mac at work.

Well, state of the art for a Mac around 1990.

Even more, he needed the time spent with Mac and his wife.

God help her, what she was going to do with him and Mac?

Mac is going out with me today to her house.

By then, Mac has come to terms with his situation and is ready to move on.

Mac and I go back a ways, you know that.

And really that should be turned off on the Mac.

And yes, it will even be available on the Mac.

It is on a Mac, so what are you even talking about?

All of this has been possible on the Mac as well.

Are you using it on a mac by any chance?

If the woman had shot Mac, she would have done it.

Mac looked up at me, as I stood before him.

Mac thought, a whole five days and they'd come no further than this.

I use my Mac all the time - more or less 24 hours a day.

She could see so much more now that they were no longer with Mac.

In many ways the Mac is not better, just different.

Mac has been having some problem in the last week.

I have not found anything as good on the Mac.

Hours later she once again found herself alone in a room with Mac.

He and Mac heard the phone at the same time.

Now Mac for sure heard a voice from the back.

We pretty much know what will be in the next Mac.

I am getting the Mac for free, if you will.

The 7300 is the same as on my Mac at work.

Well, state of the art for a Mac around 1990.

Even more, he needed the time spent with Mac and his wife.

God help her, what she was going to do with him and Mac?

Mac is going out with me today to her house.

By then, Mac has come to terms with his situation and is ready to move on.

Mac and I go back a ways, you know that.

And really that should be turned off on the Mac.

And yes, it will even be available on the Mac.

It is on a Mac, so what are you even talking about?

All of this has been possible on the Mac as well.

Are you using it on a mac by any chance?

If the woman had shot Mac, she would have done it.

Mac looked up at me, as I stood before him.

Mac thought, a whole five days and they'd come no further than this.

I use my Mac all the time - more or less 24 hours a day.

She could see so much more now that they were no longer with Mac.