However, unfractionated heparin and low molecular weight heparin do not cross the placenta.
Low molecular weight heparin is used to reduce or at least prevent enlargement of a thrombus, and is also indicated before any surgery.
Aspirin and low molecular weight heparin should be administered, and possibly warfarin as well.
Low molecular weight heparin is detected at higher concentrations.
It is a smaller molecule than low molecular weight heparin.
Usually, warfarin is avoided in the first trimester, and a low molecular weight heparin such as enoxaparin is substituted.
Standard therapy is to start treatment with injections of low molecular weight heparin and Coumadin pills.
Patients tend to respond very well to anticoagulation such as coumadin or low molecular weight heparin but may become symptomatic when treatment is withheld.
Low molecular weight heparin also disrupts rosette formation and may have a lower risk of bleeding in malaria.
Some studies have shown that HIT is less common in those receiving low molecular weight heparin.