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We chose 6 years for the washout period as a compromise.
As in the first study, volunteers switched treatments after a one-week washout period.
After a one-week washout period, they switched to the active or placebo treatment for another four weeks.
After the washout period serial measurements of fluorescence alternating with absorbance were taken.
The washout periods were seven days.
If they improve substantially on the placebo during this "washout period," they are excluded from the trial.
After a seven day washout period, the same measurements were taken under the same conditions after intake of the other treatment being studied.
The varying placebo rate is due to suicide attempts during the washout period being placed in the placebo groups.
A run-in period is sometimes called a washout period if treatments that participants were using before entering the clinical trial are discontinued.
When switching from MAOIs to bupropion, it is important to include a washout period of about two weeks between the medications.
There has also been evidence of prolonged budiodarone cardiac effect days after drug discontinuation as the atrial fibrillation baseline measurements were not reached in washout periods.
Using the PKQuest PBPK results, 65% of the halothane should have been recovered during a 5 day washout period relative to the total uptake.
Each patient was given, in double-blind randomised order, loperamide-N-oxide (3 mg orally twice daily) and placebo for 14 days, separated by a washout period of 14 days.
However, this analysis included only 6 studies out of the over 2,000 that have been done, involved just 2 medications, and did not involve studies with placebo washout periods typically used as controls.
We thought a longer washout period would have greatly restricted the age range under study and a shorter washout period would have had a much more limited effect.
In another study, Glycine propionyl-l-carnitine or a placebo was provided to resistance trained men for four weeks each, with a two-week washout period between each four-week period, using a double blind design.
Five of the women were on ERT before the study and had their ERT sleep evaluation first and the non-ERT evaluation two weeks after a washout period.
The report concluded that "[t]he results of this study indicate that eight weeks of 6-OXO supplementation had no effect on body composition or clinical safety markers, but incompletely inhibited aromatase activity and significantly increased endogenous DHT levels that were attenuated after a three-week washout period".