The prednisone actually causes a spurt in virus replication, he said.
Antiretroviral drugs are highly effective at controlling virus replication, but they also have several drawbacks.
Local virus replication will result in viremia, spreading the infection into other tissues and organs.
Those parts of the cycle that apply only to virus replication and assembly/transmission are shown by the green arrows.
Interferons are named after their ability to "interfere" with virus replication inside host cells.
If you get six hours of virus replication because you skip a dose, that is going to move onto viral resistance fairly quickly.
The antiretroviral therapy drugs will not control the virus replication as effectively or protect the immune system.
When this happens, the drug no longer effectively controls virus replication or protects the immune system.
During drug therapy, low-level virus replication still occurs, particularly when a patient misses a dose.
Consistent with this, exogenous protease was not required for virus replication in vitro.