NO produced by endothelial cells affect smooth muscle cells of the vessel wall and modulate the vascular tone toward vasodilatation.

Potassium channels may also be involved in maintaining vascular tone.

He is the discoverer of eNOS, a key regulator of vascular tone.

The pitfall of all noninvasive technologies is change in vascular tone.

And there is no reason to believe that only the balance between quantities of prostacyclin and thromboxane is the determinant factor for vascular tone.

In the peripheral nervous system (such as in the gut wall) serotonin regulates vascular tone.

The endothelium regulates local vascular tone and integrity through the coordinated release of vasoactive molecules.

Thus, all three NOS isoforms could contribute to modulation of pulmonary vascular tone.

Nitric oxide from hemoglobin helps determine vascular tone, Dr. Stamler said.

Other factors that affect vascular tone, like hormones and the sympathetic nervous system, operate on a bodywide scale.