A molecule that prompts the replication of these cells would allow the use of higher doses.
Stomach upset has been reported as a common side effect with the use of therapeutic doses of black cohosh.
Some 80 percent of adverse reactions occur after the use of recommended doses, which vary depending on the product.
"Now we are exploring the use of lower doses of verapamil taken orally."
Serious illness, including liver damage, has occurred even with short-term use of normal doses.
Biological approaches include the use of herbal medicines, special diets or very high doses of vitamins.
The disorder has been associated with severe infections and the use of high doses of antibiotics.
It includes the use of large doses of vitamins and is commonly called megavitamin therapy in general.
Both drugs are dosed at 1.5 to 2.5 mg/kg, with literature supporting the use of higher doses.
Medical treatment in 1880, included the use of intravenous doses of a drug called pilocarpin.