Whereas in the lowlands of upper Mesopotamia he might hope to find ripe grain to buy.
Mardin is one of the oldest settled areas in upper Mesopotamia.
He was a confederate of Shamshi-Adad of upper Mesopotamia.
The empire included a large part of Anatolia, north-western Syria and north west upper Mesopotamia.
The principality ruled western Iran and upper Mesopotamia.
By 526-527, overt fighting between the two empires had broken out in the Transcaucasus region and upper Mesopotamia.
Overt Roman-Persian fighting had broken out in the Transcaucasus region and upper Mesopotamia by 526-527.
In the long series of wars between the two powers, the frontier in upper Mesopotamia remained more or less constant.
Ekallatum was an ancient Assyrian city of upper Mesopotamia.
The history of upper Mesopotamia in this period is documented in the archives of Mari, Syria.