In lung cancer, cavitation can represent central tumor necrosis (tissue death) or secondary abscess formation.

Anterior uveitis is an uncommon presentation and occurs due to tumor necrosis.

Administration of acemannan has been shown to increase tumor necrosis and prolonged host survival; the animals have demonstrated lymphoid infiltration and encapsulation.

These hemorrhages are related to tumor necrosis, vascular invasion and neovascularity.

It is uncommon to see tumor necrosis, but when it is present, it is diagnostic of cancer.

These approaches often produce central tumor necrosis, reduction in tumor size, and relief of pain, but the benefits are usually transient.

Plinabulin works by interrupting tumor blood flow via disruption of the tumor's vascular endothelial cells resulting in tumor necrosis.

In certain trials, extent of tumor necrosis is used to determine postoperative chemotherapy.

In general, if tumor necrosis exceeds 90%, the preoperative chemotherapy regimen is continued.

If tumor necrosis is less than 90%, some groups have incorporated drugs not previously utilized in the preoperative therapy.