Busulfan can control tumor burden but cannot prevent transformation or correct cytogenic abnormalities.

Such studies require a simple mechanism by which to evaluate tumor burden.

Since most patients with epidemic KS do not die from the disease, factors besides tumor burden are apparently involved in survival.

Terminal necropsy was performed at age 23 weeks or when tumor burden became too great.

Some women will be cured and others will have the tumor burden (which includes spread) reduced by earlier surgery.

Mice were sacrificed at 13 weeks of age for the determination of tumor burden.

The tumor burden of the untreated control group at the end of the study was 146 mm 3.

As observed in the intervention trial, tumor burden in the group receiving the combinatorial treatment had remained virtually unchanged.

It does not really quantify tumor burden or extent unlike staging systems used in other cancers.

The compound was tested out in xenograft mice that had multiple human tumors, and the result was reduced tumor burden.