In a trial of 2000 patients on taking sertindole, 27 patients died unexpectedly, including 13 sudden deaths.

For example, a 1982 trial of 175 patients found tumor size had increased in all but one patient.

The safety and effectiveness of Erwinaze was evaluated in one clinical trial of 58 patients.

In a Phase I clinical trial of three patients, two showed no improvement and one of them had some improvements.

Using combination chemotherapy, only 10% to 20% of patients survived even 3 years in a trial of 118 patients.

In a trial of 1,000 patients, Riluzole did not appear to lessen the severity of the symptoms.

When InterMune then did its own large trial of 330 patients, the drug did not improve lung function.

The authors analyzed 23 trials of 2774 patients.

One randomized controlled trial of 157 patients with chronic migraine was published in October 2012.

He said earlier trials had shown dose-related side effects and the company had lowered the dosage accordingly for its current trial of 740 patients.