This is a tremendous setback for Orange County.

"They overcame tremendous setbacks and asserted themselves as individuals at a time when the world did not have that expectation of women."

She added that "statehooders received a tremendous setback, especially when you consider the economic resources they had at their disposal."

Their departures would be a tremendous setback to the company.

"The market took a tremendous setback."

He said: 'If we were to win it would be a tremendous setback for Denmark, maybe even terminal.

"It would be a tremendous setback if he reinjured himself," Torre said.

That scenario, some team executives feel, would be a tremendous setback for the N.F.L.

Obviously, it was a tremendous setback, but I always knew people would have an opportunity to see my talent.

Between 1926-1928, Yalobusha County suffered two tremendous economic setbacks.