In the Survival Study, children could move from one treatment group to the other by moving between clusters with different treatment assignments.

Risk-based treatment assignment is an important therapeutic strategy utilized for children with ALL.

Consequently, all treatment assignments in the task add up to 100 points or more.

To achieve this ranking, the study allocation must be blinded to the physician both before and after the randomization and the treatment assignment take place.

Based on this knowledge she would make the following treatment assignments:

The treatment assignment was not random, which makes the result hard to interpret.

"It eliminates bias in treatment assignment," specifically selection bias and confounding.

A good randomization procedure will be unpredictable so that investigators cannot guess the next subject's group assignment based on prior treatment assignments.

In that case one should investigate if there were any deviation from random treatment assignment that may have affected cancer death rates.

A procedure in which one or more parties to the trial are kept unaware of the treatment assignment(s).