"Congenital heart disease was a totally unexplored area at the time she was running her clinic," Dr. Lurie said.

They were the first pioneers in the history of the human race that had the challenge of a totally unexplored, alien environment to study.

But the battle of Helena and Bodey over Dorothea intimates agendas Williams left totally unexplored.

We're in a totally unexplored environment, you idiot, and we have to watch ourselves at all times!

We are in a functioning, totally unexplored prison here, and everything has to be approached with caution.

"It's a totally unexplored, unchartered arena," he added.

Something catastrophic is taking place in the distant and totally unexplored depths of Africa, from where the mighty river springs.

To set them down, as on a totally unexplored planet, was unlike any previous knowledge Kai had of EEC.

A Command decision, out here in a totally unexplored arm of the galaxy?

He felt like a man following arrows deeper and deeper into a frightening but fabulous and totally unexplored cavern.