The bishop asked her whether she would take on the task, and she replied, "My heart is not totally closed to it."

I gave no thought to trying to open it, because even in my childhood few doors were totally closed to me.

The business class and the establishment are not totally closed to outsiders.

She was totally closed in on herself; some people handled stress that way, by almost shutting down.

Often her eyes seemed totally closed and always she looked shy, even scared.

However, it does continue to apply to totally closed (isolated) systems.

In 1990, land reclamation of garbage in the place was totally closed.

That's what happened in Rwanda - it was too much too quickly for a system that had been totally closed.

The street blocks in which the festival take place are totally closed to traffic for the weekend.

Later I will justify myself to you, if your minds are not totally closed.