Surgery is often the treatment of choice, total resection is often possible, the medical team will advise on treatment depending on factors such as:

The prognosis for patients with myxopapillary ependymoma is good with the possibility of more than 10 years of survival after total or partial resection.

Follow-up studies indicate that gross total resection results in long-term survival in patients with DIA and DIG.

Grade II tumors can behave variably and there is no standard of whether to give radiotherapy following a gross total resection.

Near total resection does not seem to influence the cure rate, so gross total resection is not necessary and can increase the risk of complications from surgery.

After total resection the 10-year survival rate is 90%.

Repeat attempts at gross total resection are difficult, and complications are more frequent than with initial surgery.

For patients who undergo gross total resection with microscopic residual disease, the value of adjuvant radiation therapy is controversial.

For children with initially unresectable tumors, delayed gross total resection followed by 36 Gy beam RT provides an excellent likelihood of local control.

Studies on adult patients demonstrated that gross total resection or even extended lesionectomy could greatly improve seizure prognosis.