They work by preventing platelet aggregation and thrombus formation.

For example, thrombus formation is a debilitating side effect of high shear stresses created by the design of the valves.

This lack of movement of blood can lead to thrombus formation (blood clotting).

The hemostasis system becomes temporarily biased towards thrombus formation, leading to a prothrombotic state.

Infarct expansion may result in cardiac rupture, aneurysm, and thrombus formation.

An antithrombotic agent is a drug that reduces thrombus formation.

On the converse, thrombus formation must be inhibited at times when there is no damage to the endothelium.

Over the past few decades, considerable research effort and capital has been directed towards developing materials that do not cause thrombus formation when exposed to blood.

As well, some chest tubes are coated with heparin to help prevent thrombus formation, though the effect of this is disputed.

It works by reducing platelet aggregation and thrombus formation.