The virus's harmful genes are stripped out and a therapeutic gene inserted in their place.
Various vectors have been developed to carry the therapeutic genes to cells.
They have the capacity to deliver a large amount of therapeutic genes repeatedly, and it is convenient to produce them on a large scale.
In Gelsinger's case, the goal was to introduce therapeutic genes into his liver cells.
The current commercial techniques for activating therapeutic genes require the continual application of a drug to keep the gene active.
C1 A drug as an on-off switch for therapeutic genes.
This would be followed by insertion of a therapeutic anticancer gene.
Onyx is also studying ways to use the virus to carry therapeutic genes to tumor cells.
Dr. von Kalle's hypothesis is that a second genetic change came from the therapeutic gene itself.
They hope to use it to slip therapeutic genes into people's cells to treat inherited diseases, heart disease and cancer.