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The use of falsified medicines can result in therapeutic failure and can put lives at risk.
General practitioners and dermatologists should now consider propionibacterial resistance as a cause of therapeutic failure.
Hence, dipyridamole is a pharmacological success, but a therapeutic failure because of the coronary steal phenomenon.
Regrettably, they neglect other reasons for therapeutic failure, which may range from rank inexperience to avoidable error to faulty technique to the limits of science.
Non-compliance is the principal factor in therapeutic failure and studies report over one-third of treatment failure is due to this (Taitz et al.
In therapeutic failure, a microbiologic culture should reveal the continued presence of an infectious organism, whereas in paradoxical IRIS, follow-up cultures are most often sterile.
Adjunctive folinic acid with trimethoprim-sulfamethoxazole for Pneumocystis carinii pneumonia in AIDS patients is associated with an increased risk of therapeutic failure and death.
Four of the 28 patients died within 48 hours of the initiation of colistin; these patients were not included in the analysis because they were not considered true therapeutic failures.
Toner GC: Early identification of therapeutic failure in nonseminomatous germ cell tumors by assessing serum tumor marker decline during chemotherapy: still not ready for routine clinical use.
Therapeutic failures and persistent bacteremia have been reported with chloramphenicol, and successful treatment with this drug does not appear to eliminate the patient's risk for development of the eruptive phase.
The F.D.A. has repeatedly said there have been no documented cases in which an approved generic substitute has caused a therapeutic failure - in other words, the generics work as they are supposed to.
The F.D.A. said the letters included "misleading and unsupported allegations," which were "predicated on the danger of substituting one anticonvulsant drug for another, alleging therapeutic failures and other problems upon substitution."
That chthonic position makes the proteins difficult to tinker with or repair, difficult to target with drugs or therapies, which is why the story of fundamental cancer research has thus far been one of intellectual triumph, but therapeutic failure.
The study documented therapeutic failures in three patients with cystic fibrosis after pharmacists substituted capsules of a generic drug, pancrelipase, made by Anabolic Inc. of Irvine, Calif., for the brand-name drug Pancrease manufactured by McNeil Pharmaceutical.
Health care professionals and consumers may report side effects, product quality problems, product use errors, or therapeutic failure with the use of medical products to FDA's MedWatch Adverse Event Reporting program either online, by regular mail, by fax, or by phone.
By initially accepting her reading of events, Freud was able to remove her cough symptom; but by pressing her to accept her own implication in the complex interfamily drama, and an attraction to Herr K, he alienated his patient, who abruptly finished the treatment after 11 weeks, producing, Freud reported bitterly, a therapeutic failure.