Create the root node and the layer of the target variable.

Then one or more other variables are changed repeatedly, subject to the specified constraints, until you discover the best values for the target variables.

No statistically significant difference of the primary target variable between sarizotan and placebo could be demonstrated.

But both these target variables are also influenced by variables outside the direct control of the authorities.

With monetary policy the target variables may consist of some measures of the money supply or interest rates.

Instruments (or techniques) enable the authorities to influence target variables.

It is through changes in instruments that the fiscal authorities influence the levels of taxation and government expenditure, the two target variables.

Macroeconomic objectives must be sensitive to changes in target variables.

The authorities must be able to control target variables via instruments.

A lag exists between the change in instruments and their effect on intermediate target variables.