When flies are fed doxycycline, rtTA binds to target sequences in the synthetic tet-on promoter in the PdL P element.
They also target sequences that control subcellular localization.
Mitochondrial matrix targeting sequences are rich in positively charged amino acids and hydroxylated ones.
By targeting sequences in gene promoters, saRNAs readily induce target gene expression in a phenomenon referred to as dsRNA-induced transcriptional activation (RNAa).
Zinc finger domains can be engineered to target desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes.
Numerous selection methods have been used to generate zinc-finger arrays capable of targeting desired sequences.
In genotyping reactions where two probes were present in a single reaction, the secondary primers were designed to anneal to target specific sequences shared by both OCPs, in the 5' and/or 3' arms (Table 1).
Circular permutation assays of DNA bending induced by binding of GST-pou[c] to target sequences.
Industrial drugs that are designed as protease and reverse transcriptase inhibitors are made such that they target specific sites and sequences within their respective enzymes.
It is classified as a ternary complex factor (TCF), a subclass of the ETS family, which is characterized by a common protein domain that regulates DNA binding to target sequences.