TopoIIα in tumour cells is a target enzyme of some anticancer agents.

Two facts led Dr. Jacobs's team to conclude that catalase was not the target enzyme.

Pharmaceutical companies wish to combinatorially screen drug candidates against target enzymes.

The major route of metabolism is by its target enzymes via cholinesterase-mediated hydrolysis.

In drug design it is important to consider the concentrations of substrates to which the target enzymes are exposed.

Some reversible inhibitors bind so tightly to their target enzyme that they are essentially irreversible.

The kinase then phosphorylates target enzymes, regulating their activities.

Mevastatin was demonstrated to be an unusually potent inhibitor of the target enzyme and of cholesterol biosynthesis.

Armed with new knowledge of the biology of their target enzyme, chemists should be able to design or select potentially resistance-proof drugs.

The target enzyme in H.I.V. cannot distinguish the difference, but human enzymes can, he said.