When taking tamoxifen, you will need a pelvic exam every year.
It is already clear that not every woman can take tamoxifen.
Women younger than 50 years who have a high risk of breast cancer may benefit the most from taking tamoxifen.
They wanted to give the women in the placebo group the chance to take tamoxifen, too.
American studies showed that in 1,000 women over 60 who did not take tamoxifen, there would be one case of endometrial cancer per year.
But there are no answers yet for women who stopped taking tamoxifen six months ago or longer.
Women who take long-term tamoxifen are at higher risk.
Women are usually advised to take tamoxifen for five years after a breast cancer operation.
But too few women with breast cancer are taking tamoxifen, the Oxford team said.
The cancer rate in the group taking tamoxifen dropped by 50 percent.