It has been suggested that this is not a separate disorder, but the final result of several vascular systemic disorders.

Aphthous-like ulceration may occur in association with several systemic disorders (see table).

Some physical illnesses, known as systemic disorders, also have a similar quality.

Many diseases affecting the kidney are systemic disorders not limited to the organ itself, and may require special treatment.

There had been talk of sarcoidosis, a chronic systemic disorder that tends to afflict women in their 30's.

It is a systemic (whole body) disorder principally affecting synovial tissues.

This form of the disorder is usually found in association with another underlying systemic disorder.

Mononeuropathy is most often caused by injury, although systemic (body wide) disorders may cause isolated nerve damage.

Kidney stones can occur as an isolated medical event, but often are part of a systemic biochemical disorder.

As these diseases are often associated with systemic medical issues, proper management of the systemic disorders is appropriate.