Based on the meiotic process, the syndrome may occur in two ways.

The syndrome generally occurs within the first 20 years of life.

This syndrome usually occurs for no obvious reason and is uncontrollable.

The syndrome may occur at any age, but is most common in people of both sexes between ages 30 and 50.

The syndrome also can occur in children; it affects women more often than men.

No one knows for certain why this syndrome occurs.

The syndrome can also occur weeks after a serotonin-raising drug has been discontinued.

It is not well understood why this syndrome occurs.

This syndrome can occur in any age, but mostly in between the ages of 30 to 60.

In 1 out of 400 untreated cases Lemierre's syndrome occurs.