"So doing it after June 8 could substantially shorten the term of patent," Mr. Kirk added, since patents can often take longer than three years to process.

By generating vast power, they could substantially shorten a Mars voyage and enhance its feasibility.

If the antibiotic substantially shortens TB treatment, which now typically lasts six months, the company will make millions of doses and sell them at low prices to poor countries.

(Lithium batteries substantially shorten the wait, but so far only on units designed for them.)

The tragedy is that, at the moment when a massive explosion of agitation in Britain for a Soviet alliance might have substantially shortened the coming war, the popular movement was inert.

In the 20th century their contribution was so important that historians judge it substantially shortened the most terrible events in the history of mankind.

Claude had also solved two technical problems that substantially shortened the working life of neon and some other gas discharge tubes, and effectively gave birth to a neon lighting industry.

This link will substantially shorten the travelling time between the eastern and western sides of the southern tip of the PRD.

The port substantially shortens the overland transport of cargoes to and from the southern and central parts of the country.

Oral antibiotics such as trimethoprim/sulfamethoxazole (TMP/SMX), cephalosporins, nitrofurantoin, or a fluoroquinolone substantially shorten the time to recovery with all being equally effective.