White, despite the substantial disadvantage of moving second, apparently is in the lead now due to the reduced mobility of black's first-row checkers.

Matilda was the king's only legitimate child, but as a female, she was at a substantial political disadvantage.

Cricket's association with the mother country was a substantial disadvantage here.

The dealer-focused companies have felt themselves to be at a substantial disadvantage in terms of price comparison.

Even then they were at no substantial tactical disadvantage.

The Boers carried no bayonets leaving them at a substantial disadvantage in close combat, which they avoided as far as possible.

"But if we're not allowed to provide long-distance service we're being put at a substantial disadvantage."

And, of course, even if statewide expenditures were better equalized, poorer states would continue to be at a substantial disadvantage.

In addition, the panel said, doctors who choose to treat Medicaid beneficiaries may be at a "substantial economic disadvantage relative to their peers."

This creates a substantial disadvantage for the second player for beginning players, since the second player starts on the right side of the screen.