Invading Iraq could involve substantial casualties and possible long-term occupation responsibilities.
There was a series of disastrous explosions from 1904 to 1910 at the coal mines near Trinidad which resulted in substantial casualties.
The Danish forces have suffered substantial casualties including 24 deaths up till September 2009.
The American rearguard were able to inflict substantial casualties on their overconfident pursuers.
Mr. Clinton has acknowledged that if the mission brings substantial casualties, it could cost him re-election.
The raid was a success but the British force suffered substantial casualties as they returned to their landing-point.
The Norwegian army was thus routed, and in the mad dash back to their ships they suffered substantial casualties.
Could she explain her decision to return to Xavier system and try to fight a battle against odds, with no senior officers and substantial casualties?
The chances of substantial casualties and involvement in a prolonged new war are far higher in the first case than in the second.
"Once they have taken substantial casualties, they will fall into chaos and we can break them."