The stress took a toll on his health, and he died of a heart attack in 1846.
But the stress of their jobs is taking a toll.
Even though he enjoys his work, stress has taken its toll.
Given time, stress can take a toll on your physical health.
The physical and emotional stress of his great play over the previous 15 years was taking its toll.
It's not an easy job, and its stresses can take their toll.
The stress was taking a toll on all of them.
And stress, as we all know, can take years off your life.
The stress of treatment can take a toll on relationships.
But stress takes a huge toll on Americans every year.