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Peak plasma concentrations of the drug are reached within one hour.

Or put another way, the time that it takes for the plasma concentration to fall by half from its maximum levels.

Peak plasma concentrations occur between 30 and 120 minutes after administration.

Peak plasma concentrations are reached eight to 12 hours after oral administration.

Peak plasma concentrations are attained within the first hour of administration.

This transport system can also be saturated if the plasma concentrations of the drug are high.

Where: is total amount of the drug in the body and is the drug's plasma concentration.

Therefore the dose required to give a certain plasma concentration can be determined if the V for that drug is known.

It enters the central nervous system in proportion to its plasma concentration.

In Dresser study (2006), plasma concentration of 24 subjects was obtained.