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Peak plasma concentrations of the drug are reached within one hour.
Maximum plasma concentrations are reached after one to three hours.
Or put another way, the time that it takes for the plasma concentration to fall by half from its maximum levels.
Peak plasma concentrations occur between 30 and 120 minutes after administration.
Steady state plasma concentrations are achieved within one to three days.
Peak plasma concentrations are reached eight to 12 hours after oral administration.
This transport system can also be saturated if the plasma concentrations of the drug are high.
Following oral administration, it takes about 1.5 to 2 hours to reach maximum plasma concentrations.
The solid line is the model plasma concentration and the open squares are the experimental data.
Where: is total amount of the drug in the body and is the drug's plasma concentration.
This, in turn, could produce drug plasma concentrations less than the desired therapeutic range.
It enters the central nervous system in proportion to its plasma concentration.
Plasma concentration of amylase was not different from the control value (Fig 4).
Definition: the time required for drug plasma concentration to decrease by 50% after stopping administration.
Its maximum plasma concentration (Cm) is reached 1-2 hours after oral administration.
The main reasons for determining a drug's plasma concentration include:
Therefore the dose required to give a certain plasma concentration can be determined if the V for that drug is known.
Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours.
The peak plasma concentration is reached 4.5 hours after oral dosing.
Because of the long half-life it could take days before the plasma concentration is decreased to a safe value.
Following an oral single dose of 20 mg peak plasma concentrations are reached within 1 to 2 hours.
First a low-glucose plasma concentration, then the heart, now the gallbladder.
Maximum Plasma concentration was achieved one hour post dose and declined rapidly.
This results in a lower peak plasma concentration.
When orally administered, peak plasma concentration occurs after 1-2 hours.