Nothing they could say would make the slightest difference to him.
Nothing he could say now would make the slightest difference.
It wouldn't have made the slightest difference if we had found out earlier.
It hasn't made the slightest difference to the human race.
I don't think it would make the slightest difference in the case of a child.
And no visit now would ever make the slightest difference.
It never seemed to make the slightest difference to their numbers the next morning.
I don't see that it makes the slightest difference to us.
Nothing that you do of your own free will can make the slightest difference in what happens here.
And now I have discovered slight differences in the blood of different patients.