Polymodality is the feature of a single receptor of responding to multiple modalities, such as free nerve endings which can respond to temperature, mechanical stimuli (touch, pressure, stretch) or pain (nociception).
It narrows the definition of antagonism to consider only those compounds with opposing activities at a single receptor.
The findings about the single receptor's role might make it possible to design molecules that mimic key parts of the receptor.
A single receptor cannot analyze the wavelength of the light it receives: it simply acts as a quantum counter, but the information about the wavelength identity of the quantum is lost on absorption.
Promiscuous refers to the biochemistry and pharmacology concept of how a variety of molecules can bind to and elicit a response from single receptor.
Drugs which affect one single mediator and/or block one single receptor are unlikely to be helpful.
Additional tests showed that these two peaks are a function of a single receptor in the eye.
Transfer of alpha and beta TCR genes shows MHC-restricted antigen recognition by a single receptor.
However, unlike the immune system, which generates diversity through in-situ recombination, every single olfactory receptor is translated from a specific gene; hence the large portion of the genome devoted to encoding OR genes.