Because of its history, the city displays a development pattern which does not focus on a single centre.
A retrospective analysis of 273 patients observed at a single center.
The surface of this world was one single industrial centre.
As a result, these "cities" have no single centre, but several.
The art world no longer has a single center, or even two or three.
Now that the convention was behind us, we needed much better coordination among all the forces, with a single strategic center.
The service said it planned to consolidate testing at a single center.
He got a hit, a single to center in his first major league start the next day.
We do not have a single centre which could react to disaster situations.
Finally, because the study was limited to a single center, the results may not apply to other patient populations.