We want to see them do some more significant things.

Of course, she couldn't remember exactly what that significant thing was.

It seemed she did, after all, know a few significant things about him.

The most significant thing was to win the game and to make sure we would be playing next week.

"Even if they just think about it, that in itself is a significant thing."

The significant thing is that she did not move at all.

It was not a significant thing in the first place.

Three significant things are to be seen in the story.

In the long run that will be the most significant thing.

There was another significant thing happened on the back nine, as well.