"Pat created a lot of opportunities for young people in this business to learn and have significant responsibilities."

"Those flights are important not just to us, but to allies to whom we have significant responsibilities in the region," one said.

They also have significant managerial responsibility: one such woman is an elected member of our management committee.

Accordingly, they are being given positions of significant responsibility and trust.

In a non-retail business, this would be a position of significant responsibility.

Company officials say they do not fear the suit and deny any significant responsibility for environmental damage.

In the model, the traffic contractor has a significant developing responsibility.

You have taken on a significant responsibility in this area.

With their great power and influence in the markets, there should also be significant responsibility.

Clearly, nations themselves must bear a significant responsibility, but no nation can solve the environmental problems by itself.