Big movements in the oil price have significant ramifications around the world.
But for others, too, there are significant political ramifications.
This first "wave" as it became known had some significant ramifications.
Although many state officials were reluctant to comment on the ruling without further study, most agreed that the order had significant ramifications for student rights.
This is a very serious problem that could have very significant ramifications at any point.
Breaking these would have significant ramifications for electronic privacy and security.
One cannot deny that the decision on whether or not to use sampling will have significant political ramifications.
The staffing issue had perhaps its most significant ramifications in the police administration division.
This has been discussed previously - there are significant legal ramifications.
India has experienced a similar phenomenon, with significant negative ramifications for its economy.