"It really has been a significant hardship on the many people who work here."

Although it would cause significant financial hardship for Swift and his clerk, he decided to run the chambers himself.

For us both to lose a day's pay, in the last payment before Christmas, is a significant hardship.

And one day without pay is significant hardship?

This meant waiting in Toronto about three hours for the next flight, not a significant hardship.

The Great Depression of the 1930s caused significant hardships for the school district and the teachers.

The criminal justice system responds to a substantial number of events that do not produce significant hardship to individual citizens.

Rockford had faced significant financial hardship during the 1871 season, including travel cost, and did not make a profit.

This is going to be a very significant hardship on the region's economy.

A worst case in Europe could lead to significant hardship for emerging economies, the report said.