It was the mayor's second major defeat this week on a signature initiative of his administration.

Their commitment on this area has led to the creation of a substantial number of signature initiatives and collaborations with significant partners.

Bush expressed disappointment upon the defeat of one of his signature domestic initiatives.

His signature environmental initiative is regarded as weak, and legislators are debating how much it should be toughened.

Two of Mr. Bush's signature educational initiatives are also having problems.

But he can't afford to allow his signature initiative to go down in flames.

Funding for faith-based organizations in the U.S. centers around several signature initiatives including:

She inherited health care reform, once more taking command of the signature initiative of her husband's ad-ministration as she had with education during his governorship.

The governor's budget document referred to this proposal, which would have cost the state $105 million a year, as a "signature initiative."

But signature initiatives have a way of becoming disposable when budget talks begin to resemble wrestling matches.