PMF is associated with more severe symptoms and respiratory impairment than simple disease.

Symptoms and pulmonary function testing relate to the degree of respiratory impairment, but are not part of the diagnostic criteria.

Significant respiratory impairment can be demonstrated in these people by pulmonary function testing.

In 1988 an expanded definition was proposed which quantified physiologic respiratory impairment.

The major exception are patients left with severe residual respiratory difficulties, who may experience new severe respiratory impairment.

No significant association between the type of respiratory impairment and the degree of dyspnea was found.

Disease symptoms, which most often begin about age 3, include muscle weakness and deterioration, respiratory impairment, heart problems, joint stiffening and spinal curvature.

Drowning is the process of experiencing respiratory impairment from submersion/immersion in liquid.

Osteoarthritis, gall bladder disease, sleep apnea, respiratory impairment, diminished mobility, and social stigmatization are associated with obesity.

They should be used cautiously (or not at all) for respiratory impairment.