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This woman produced 100 times the normal amount of renin.
Tests for renin levels are already available through commercial laboratories.
Plasma renin activity was low and changed with treatment (table).
Direct renin inhibitors are used to lower high blood pressure.
The two most important ones that it makes are erythropoetin and renin.
In addition, knowing renin levels could help doctors determine treatments for people with heart disease.
As many as a third of people with high blood pressure have normal renin levels.
Direct renin inhibitors should not be used by pregnant women.
Therefore, doctors have been looking for a drug to inhibit renin directly.
In addition, tests for renin levels are complicated and involve additional health care costs.
In some people, it may be normal to have high blood levels of both renin and aldosterone.
Therefore, renin inhibitors can be used for the treatment of hypertension.
They emphasized that it could be very costly to suddenly start treating high renin levels.
While calling for further studies, he said "it is quite impressive that the heart attacks occurred in the high renin patients."
Renin regulates blood pressure and the amount of salt the body retains.
The most common side effect of direct renin inhibitors is diarrhea.
Before taking a direct renin inhibitor, tell your doctor if you have kidney problems.
So what in the world could cause the kidney to produce so much renin?
It acts to regulate the levels of renin protein produced in the cell.
Two clases of drugs widely used to treat high blood pressure also lower renin levels.
Direct renin inhibitors are the newest type of medicine for high blood pressure.
In addition, none of the subjects in the study with low renin levels and no other risk factors had heart attacks.
But although high renin levels cause high blood pressure, they are not the only cause.
For years, some investigators have regarded renin as a very likely culprit in causing heart disease.
A renin test is often done at the same time as an aldosterone test.