Averaging nearly seven yards per carry, he led the Gators to a 9-2 record, the first time the Gators had achieved nine regular-season wins.
It is second overall in playoff wins and tied with the Miami Dolphins for most regular-season wins.
Villanova's 25 regular-season wins tied a school record.
Week 12: Surpassed John Elway for second place on the NFL's all-time list for regular-season wins by a quarterback.
But those successes all came with Manning, who led the Colts to a league-record 115 regular-season wins in the previous decade and a record-tying nine straight playoff appearances.
The Yankees finish with 114 regular-season wins and 11 postseason victories (125 total - the most by any team in 123 years of Major League baseball).
They also won 38 games, the most regular-season wins in NCAA history (his 2011-12 Kentucky team would also go on to win 38 games).
DeChellis led the Lions to a 21-10 regular season in 2008-09, equalling the Penn State record for regular-season wins.
Lancaster's 142 career regular-season wins place him fourth on the CFL's career regular season wins list.
Forest City's 22-2 start, 24 first-half victories, 25 wins at home, and 46 regular-season wins all were CPL records.