First, we must take into account sequences contributing to w ( d ) that are not part of the neutral network of the reference sequence.
Selection of a reference sequence for relative compression can affect compression performance.
The idea of using multiple reference sequences has been proposed.
Additionally, a reference sequence can be designed based on statistical properties or engineered to improve the compression ratio.
A collection of human gene-specific reference genomic sequences.
By contrast, we expect connectedness to increase (or at least decrease more slowly) if the reference sequence is on the fringe of such a cluster.
Figure 3shows w ( d ) and average neutrality for examples of "fringe" and "center" reference sequences.
The proportion of As in each 50-nucleotide bin of the L1.3 reference sequence is also shown.
Frequently Asked Questions What is a reference sequence?
The screen was off but the tab was on, the reference sequence glowing softly and efficiently in red.